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White House report says Trump can usher in a "new golden age" of science

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On Tuesday, the White House Office of Science and Technology Policy (OSTP) released a report entitled "Science: A New Golden Age," in which it lays out how it has viewed science, found it lacking, and believes the Trump administration is in the perfect position to fix things. It's a bit unexpected coming from an administration that has been proposing crippling funding cuts to research and trying to enable political appointees to terminate grants awarded based on scientific merit.

The report presents itself as the spiritual successor of "Science, the Endless Frontier," a policy document that laid out the case for government-funded science in the wake of World War II. The New Golden Age (SNGA) says that, while the concepts promoted by the original remain vital, the circumstances have changed such that we need major revisions to how the government is implementing things.

The result is an odd mix. It completely ignores or glosses over many things that the administration is doing to harm scientific progress. In some cases, it identifies issues that have already been discussed as problems within the scientific community. Elsewhere, it's a mixture of political grievances, ideas without a solid intellectual foundation, and an injection of Silicon Valley's perspective on innovation (Michael Kratsios, the director of the OSTP, formerly worked with Peter Thiel). As a result, it's unlikely to have anything like the impact of "Science, the Endless Frontier."

Lacking internal coherence

The report is trying to make the case that US government-funded science has some structural problems, serious enough that they require major changes to the entire enterprise. (It also makes a positive argument, namely that developments in AI necessitate a new approach, which we'll come back to.) Some of those concerns are real and had been discussed within the research community previously.

One of the real problems it discusses is the amount of time researchers need to spend on writing grants and performing administrative tasks, taking away from their time doing research. SNGA promises to relieve this by simplifying regulations and streamlining the grant application process. But it's also remarkably vague, in that its authors do not identify a single regulation that is in need of reform.

The report also seems not to realize that it is being written by the Trump administration. One of the reasons researchers have spent so much time writing grants is a general uncertainty about funding, and that's something that the administration has dramatically increased through the haphazard termination of existing grants, by proposing massive budget cuts for science agencies, and by slowing the release of funds that had been allocated to researchers by Congress.

This lack of self-awareness permeates the document, but it's worth looking at a second example. In several instances, the report highlights the Human Genome Project as an example of the sort of project that government excels at driving. But it seems to be unaware that the project was a major international collaboration, with entire chromosomes being sequenced outside the US. Pride in the completion of the genome seems out of place from an administration that is actively trying to minimize international collaborations involving the researchers it funds.

In the same way, it highlights how the Human Genome Project required the immediate and open release of the data it generated as an example of what the Trump administration considers "gold standard science." But SNGA also decries how making results accessible to all has allowed other countries to develop industries based on advances that occurred within the US.

In short, the report lacks a perspective that's internally coherent, or consistent with the other goals and actions of the Trump administration.

The role of innovation

Another area of concern in the SNGA is that of innovation, both within science and in the translation of scientific findings to commercialization. The former has been recognized as a potential issue by the scientific community, as some measures indicate that more of the research we're doing in recent decades is incremental, and there are fewer large advances. The challenge is that these measures are controversial; it's hard to reach consensus on what counts as innovative, and some impacts of research may take longer to become apparent than most studies of the issue consider.

Yet the SNGA treats this as settled and uncontroversial. It talks a lot about how we need to promote more innovative science, and suggests a wide range of different funding models that might do so. It also says agencies will need to evaluate whether the grants they are funding are accomplishing what was intend. But it never describes how agencies should objectively measure innovativeness, so it's unclear how they can perform that evaluation, or whether the scientific community will consider their results valid.

On the flipside, this is one of the cases where SNGA's proposed solutions align with Trump administration actions, specifically its call to reduce the importance of peer review. In the new document, peer review is presented as part of the problem: "Review panels often gatekeep proposals by consensus, disincentivizing transformative ideas." And many of the new funding mechanisms it proposes include reviews by single individuals who may or may not be trained scientists. While this is likely to broaden the scope of ideas that get funded, it also seems likely that it will increase the funding of fringe ideas, something that the OSTP does not seem to consider.

(I'll note that this is consistent with Trump administration actions and not ideas; peer review remains part of what the administration is calling gold standard science, which SNGA also endorses.)

Aside from innovations within science, SNGA also is concerned with the innovation that occurs when science gets translated into products and processes by commercial interests. Here, the report decries what it terms a linear model, one where government funds basic science, which the market then takes on a one way journey to commercialization. Again, this is a case where people in science would likely agree that things are often considerably more complex. The report favors a model where commercialization is more of a conversation, as technology developments allow new scientific work that in turn leads to new or enhanced opportunities for further commercialization.

There have definitely been instances of this. A great example is the real-time RT-PCR tests that were initially used during the pandemic. Commercialization of both reverse transcriptase (the RT) and PCR allowed scientists to develop the real-time monitoring of reaction progress for their own research. Companies then commercialized hardware that simplified the process, and still other companies then developed diagnostic tests using it.

But SNGA puts all of its eggs in that basket, which is just as incomplete as the linear model. Quantum mechanics stayed trapped in physics departments for roughly 50 years before it got commercialized via lasers and semiconductors. And it's hard to imagine the timeline in which we'll end up commercializing something like the detection of gravitational waves. Neither fit the linear or conversation models of innovation.

The whole idea of government funding for basic science was the recognition that it's not possible to predict in advance which scientific findings will have commercial applications, so companies, for the most part, weren't going to do it. While SNGA is right that we should encourage those cycles of science-technology innovation when we find them, it offers no suggestions for how we identify one before it takes off and government funding becomes irrelevant. Because that is the only type of technology development it acknowledges exists, it has little to offer for any others.

Innovation in action?

Perhaps the strangest thing about SNGA is that it seems upset that scientists are highly trained specialists (although that's in keeping with the Trump budget proposals, which radically slash funds for graduate students). At its most extreme, it presents people in the field as out-of-touch elitists. "Engineering students study the theory of combustion, but few can disassemble and rebuild a combustion engine," its authors complain. "Graduate programs reward theoretical contributions measured in citation counts, but not practical applications measured in jobs and dollars."

Here, its solution is grand in scope. It views the maker community, which is mostly interested in scratching personal itches, as a sign that the US public wants to make things again. The SNGA authors figure that they would be perfectly happy making things for science. "Establish national fellowships for skilled craftspeople," they suggest, "practitioner-in-residence programs embedding machinists and technicians alongside Ph.D. researchers, and portable industry-recognized credentials in advanced manufacturing and lab techniques."

It's unclear what these machinists will be doing with the researchers. But the results will be glorious: "By rebuilding the link between science and hands-on craft, federal leadership can ensure that the economic returns of discovery, including the jobs, supplier networks, and process knowledge encoded in the hands of workers, accrue to Americans."

Its example is Detroit in its heyday, although that seems to have been a period of engineering refinements that lacked a notable scientific component. And it's unclear what scientific research center the SNGA associates with Detroit at that time.

Are there some fields that can be revolutionized by things like a 3D printer and a bit of time with the maker community? Robotics seems like an obvious choice; developmental biology does not.

Elsewhere, the report returns to the familiar claim that regulations are also stifling the potential for science-driven commercial innovation. The only specific area that's cited, however, is nuclear power: "nuclear energy stalled in America not because the physics failed, but because regulatory choices over the past half-century made building uneconomical." That is not a realistic reading of the history, as there is little indication that regulations are the primary cause of the massive delays and cost overruns that plague nuclear plant construction.

Political grievance and Silicon Valley

The complaints about regulations are one of the many cases where SNGA descends into political and cultural grievance. The most obvious case is where it detours to grumble about the role of the scientific community in the arguments over COVID school closures, but there are many additional ones.

It is once again dismissive of diversity, equity, and inclusion (DEI), while saying that all Americans with aptitude need to have access to scientific training—exactly what DEI programs were meant to ensure. It also complains that foreign students were taking slots in PhD programs from deserving Americans, while ignoring the reality that the administration's attacks on science funding have caused a number of schools to cut the number of students they admit. The fact that those foreign students often want to stay in the US to contribute to either scientific or commercial endeavors is ignored.

Grant overheads allow the institutions that host federally funded research to pay for the upkeep of the facilities where science happens. But they've been targeted by the administration, so the SNGA takes time to complain about them as well.

Most strikingly, the administration that terminated grants wholesale due to political disagreements with the subjects they were funding had the audacity to argue that it would lead the charge to "ensure that selection [of grants] rests purely on merit, not the political fashions of the day."

Beyond the political grievances, the report seems to have been shaped by OSTP head Kratsios' time as a venture capitalist. Venture capital is presented as a separate source of scientific funding from government and commercial. SNGA presents it as potentially more rigorous, since companies will fail if they're based on faulty scientific ideas. Left out is a consideration of the fact that most venture-backed companies do in fact fold; this is a track record that would be considered problematic by the authors of this report if it involved grant-backed projects.

This attitude pervades the report's approach to AI, which largely buys into the biggest hype imaginable. The reality is that we're still in the process of understanding what types of AI developments will have an impact in which fields. But SNGA envisions a future that, well, deserves to be read in full:

These pieces lay the foundation for a continuous, market-mediated, agent-based scientific economy. Imagine a funder posting a million-dollar bounty for the first validated therapeutic target for a rare disease. An agent working on adjacent problems notices a promising lead and posts a smaller bounty for replicating the finding. Other agents assess whether the problem falls within their competence, bid for the work, and contract an autonomous laboratory accessible through the internet, which runs the experiment and returns cryptographically signed results.

I guess we all have our dreams.

But it's not clear what dream the people who wrote the new report are pursuing. The Endless Frontier was a serious effort to make the case that it was in the US's national interest to fund basic science, even if there wasn't a clear commercial or national security endpoint to the work. Its audience was the policymakers that could turn that into a reality.

A New Golden Age, in contrast, is a grab bag of political grievances, half-thought-through justifications for policies the Trump administration was already pursuing, and insinuations that scientific experts are kind of annoying and should learn how to fix car engines. It's unclear who the report's audience is. Certainly not the policymakers in the current administration, since it repeatedly indicates that the decisions they are making are great already. And it's certainly not the scientists, who are currently suffering from the impact of those decisions.

A similar ambiguity exists about the goals of the document. There are lots of specific suggestions: get new funding mechanisms; don't pay attention to peer review; hire some mechanics; get industry more involved; support AI, as it will change everything. But if those added up to a coherent whole, I was not able to identify it.

"A decade from now, American researchers should look back at our work and say: 'The vital questions I could not pursue then, I am free to pursue now,'" Kratsios wrote about the document, in what seems to be the clearest indication of a goal. But A New Golden Age provides no reason to expect that they will.

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HarlandCorbin
11 hours ago
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One trip and fall and this misadministration could massively help scientific progress. And the environment. And world relations.
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Tolerating Homeless Encampments Violates the Rights of Everyone Else

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HarlandCorbin
4 days ago
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Stopped reading less than halfway through. I'm guessing that the second half didn't outright call for moving the homeless to concentration camps, but it sure was hinting that way in the first half.
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Guns and bulletproof vests: How federal agents arrested Fauci aide | Science | AAAS

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HarlandCorbin
80 days ago
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I hope gross old cheeto tan gets the same treatment from the next adminstration.
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CDC study shows COVID shot benefits; Trump official blocks release

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Under anti-vaccine Health Secretary Robert F. Kennedy Jr., scientists at the Centers for Disease Control and Prevention have been blocked from publishing a scientifically vetted study finding significant health benefits from this season’s COVID-19 vaccines, according to reporting by The Washington Post.

The move adds to longstanding concern among health experts that chaos and political interference under Kennedy—a staunch anti-vaccine activist who has long falsely maligned COVID-19 vaccines—is deeply undermining science at federal agencies and beyond.

CDC scientists and insiders told the Post that the COVID-19 vaccine study went through the agency’s standard scientific review process and was slated for publication on March 19 in the agency’s Morbidity and Mortality Weekly Report (MMWR). But acting CDC director Jay Bhattacharya blocked the scheduled publication and is holding the study, claiming he has concerns about its methodology.

Agency scientists talked with the Post on the condition of anonymity for fear of retaliation from the Trump administration.

According to a summary the Post obtained, the study concluded that between September and December of last year, healthy adults vaccinated with a 2025–2026 COVID-19 vaccine saw the risk of emergency department or urgent care visits cut by 50 percent, and the risk of COVID-19-associated hospitalizations cut by 55 percent, compared with healthy adults who did not get this season’s shot.

Bhattacharya reportedly took issue with the test-negative design of the study, which is a well-established method to examine real-world data on vaccine effectiveness. This type of observational study looks at people who have symptoms related to the disease of interest (in this case, COVID-19) and have the same test-seeking behavior. Those who test positive for the disease of interest become positive cases in the study, and those who test negative are test-negative controls. Researchers then compare the two groups based on vaccination status.

Test-negative case-control design studies have been widely used to assess the effectiveness of many types of vaccines. In fact, the CDC published a study in the MMWR last month—a week before the COVID-19 study was set to publish—examining this year’s flu shot effectiveness with the same design. But the method gained a higher profile during the pandemic, with hundreds of studies using it to estimate COVID-19 vaccine effectiveness. Analyses have found that, like any observational study design, there are potential biases, but it’s generally considered to produce reliable estimates when those biases are controlled.

Andrew Nixon, spokesperson for the Department of Health and Human Services, which oversees the CDC, told the Post in a statement that “It’s routine for CDC leadership to review and flag concerns about MMWR papers, especially relating to their methodology, leading up to planned publication.”

Nixon said Bhattacharya, who is also head of the National Institutes of Health under Kennedy, was concerned by “the observational method used in the study to calculate vaccine effectiveness” and “wants to make sure that the paper uses the most appropriate methodology for such a study.” Nixon added that the agency’s “scientific team is working to address these concerns.”

Dan Jernigan, who headed CDC’s influenza division for six years and resigned last year in protest of Kennedy’s political interference at the agency, suggested to the Post that stalling the paper fits with Kennedy’s anti-vaccine agenda.

“The secretary has already taken steps to try and remove the availability of the vaccine from children and others, so if you’re putting out an MMWR that the vaccine is effective at preventing hospitalizations and medical care visits … that message is not in line with the direction you’ve been taking with the removal of the vaccine,” he said.

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HarlandCorbin
105 days ago
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Be a shame if someone leaked the study paper...
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Improving Soda by Turning It Into Mead

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Test tasting soda mead. (Credit: Golden Hive Mead, YouTube)
Test tasting soda mead. (Credit: Golden Hive Mead, YouTube)

You can certainly just chug down that bottle of soda you purchased, but if you accept the premise that the preparation of food and drink is just a subset of chemistry, and that chemistry is fun, then it naturally follows that using soda as the basis for brewing up some mead makes perfect sense. Thus the [Golden Hive Mead] blokes over on YouTube decided to create some Coca Cola flavored mead.

Mead is essentially just water mixed with honey that is left to ferment after adding yeast, resulting in what is also called ‘honey wine’, with an ethanol content of usually between 3.5% and 20%. Since soda is mostly water and comes with its own supply of sugar for yeast to feast on, this isn’t such a crazy choice in that respect. Just make sure to remove the carbonation, as the CO2 makes the soda too acidic for the yeast to be happy.

Instead of straight honey, caramelized honey was used for extra flavor after which the brew was left to ferment for a while. For extra flavor notes aged oak, vanilla and cinnamon were added as well, to ensure that the fermentation didn’t erase those core notes of the coke. The result was apparently rather flavorful, with about a 10.5% ethanol content, receiving the full approval of both tame test tasters.

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HarlandCorbin
112 days ago
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Have a friend who started making mead from Mountain Dew back around '94. I have made mead from rootbeer. This is really nothing new!
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DOJ confirms FBI Director Kash Patel’s personal email was hacked

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Iran-linked hackers successfully broke into FBI Director Kash Patel's personal email, the Department of Justice confirmed to Reuters on Friday.

Reuters could not authenticate the leaked emails themselves but noted that the Gmail address matched an email account "linked to Patel in previous data breaches ⁠preserved by the dark web intelligence firm District 4 Labs." The DOJ suggested the emails appeared to be authentic.

On their website, the Handala Hack Team boasted that Patel "will now find his name among the list of successfully hacked victims." The hacker group taunted Patel by sharing photos of him sniffing cigars and holding up a jug of rum, along with other documents that Reuters reported were from 2010 to 2019.

"Soon you will realize that the FBI's security was nothing more than a joke," the group posted, as documented in screenshots from the website shared widely on X.

The hack came after the DOJ disrupted some of the hacker group's websites earlier this month. In a press release, Patel threatened to "hunt" down the group, which Reuters reported "calls itself a group of pro-Palestinian vigilante hackers." After detailing four attacks this month that the group had taken credit for, Patel offered rewards of up to $10 million for information on its members.

"Iran thought they could hide behind fake websites and keyboard threats to terrorize Americans and silence dissidents," Patel said. "We took down four of their operation's pillars and we're not done. This FBI will hunt down every actor behind these cowardly death threats and cyberattacks and will bring the full force of American law enforcement down on them."

The group, which Western researchers believe is "one of several personas used by Iranian government cyberintelligence units," opposes US support for Israel, Reuters reported. Their cyberattacks on US entities followed a major military attack from the US and Israel that killed Iran's Supreme Leader Ayatollah Ali Khamenei. In their press release, the DOJ quoted from emails in which the group sent death threats to dissidents in the US.

"We the Handala Hack team, the loyal followers of the supreme leader Ali Hosseini Khamenei, declare war on all the enemies of Islam in the West," the group said.

On Friday, the group confirmed on their website that the hack on Patel's email was in retaliation against the domain seizures:

Today, once again, the world witnessed the collapse of America's so-called security legends. While the FBI proudly seized our domains and immediately announced a $10 million reward for the heads of Handala Hack members, we decided to respond to this ridiculous show in a way that will be remembered forever.

Hackers claimed that their data grab included confidential information about Patel, but that could not be independently verified.

"The so-called 'impenetrable' systems of the FBI were brought to their knees within hours by our team," the group said on their website. "All personal and confidential information of Kash Patel, including emails, conversations, documents, and even classified files, is now available for public download."

The FBI has yet to comment on the hack, and Patel has not posted about it on his X account as of this writing.

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HarlandCorbin
118 days ago
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Says personal email, not government email, so probably @aol.com or something similar.

And who would have thought that ka$h4me!!! as a password would have been cracked?
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